An advisory committee for the Facilities for Illness Management and Prevention will meet on Wednesday afternoon to debate whether or not the Johnson & Johnson Covid-19 vaccine should remain paused whereas a doable hyperlink to uncommon blood clots is investigated.

The emergency assembly follows the Meals and Drug Administration’s announcement on Tuesday that it was learning six circumstances of uncommon and extreme blood clots in girls aged 18 to 48, one in all whom died. The entire girls had obtained the Johnson & Johnson vaccine earlier than creating the clots, though it is unclear whether the vaccine is responsible. As of Tuesday, greater than seven million folks in america have obtained the shot, and one other 10 million doses have been shipped out to the states, based on C.D.C. information.

Following the decision from federal well being businesses, all 50 states, Washington, D.C., and Puerto Rico on Tuesday rapidly paused or really helpful that suppliers pause the administration of the vaccine. The U.S. army, federally run vaccination websites, and a bunch of personal corporations, together with CVS, Walgreens, Ceremony Assist, Walmart and Publix additionally paused the injections.

The Advisory Committee on Immunization Practices, or ACIP, is a panel of unbiased consultants who advise the C.D.C. on its vaccine insurance policies. On the assembly, the experts will be reviewing and debating the information from the six circumstances, and listening to feedback from the general public, earlier than taking a vote on find out how to proceed. They might vote to suggest that the pause continues, for instance, or to specify that it ought to apply solely to a sure age or intercourse.

Federal officers mentioned on Tuesday that the pause may final just a few days, although it relied on what officers realized within the investigation. The pause was referred to as for partially as a result of sufferers who’ve these uncommon blood clots shouldn’t be given the usual remedy that medical doctors prescribe for typical clots.

The clotting dysfunction of concern within the vaccine recipients is totally different — and far rarer — than typical blood clots, which develop in lots of of 1000’s of individuals yearly. The six girls had not solely clotting within the mind, however a notably low degree of platelets, elements of the blood that assist kind regular clots.

The committee’s evaluation can be essential at a time when the nation is racing to vaccinate as many individuals as doable to curb the regular accumulation of circumstances, significantly as worrisome variants acquire traction. Some public well being consultants have been upset within the F.D.A.’s advice to droop the Johnson & Johnson vaccine, arguing that stopping these extraordinarily uncommon uncomfortable side effects was not worth the trade-off of slowing the vaccination marketing campaign and probably eroding the general public’s belief of vaccines typically.